Spatial Analysis of the Microcirculation in Rat Spinotrapezius Muscle Fascia

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Conference Proceeding

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The microcirculation in the fascia of rat spinotrapezius muscle is studied using a computational approach that accounts for the shear- and hematocrit-dependent rheology of blood [1]. The simulations are based on a realistic network reconstruction derived from microscopic images of the fascia. The model includes fundamental aspects about passive properties of microvessels [5] as well as active myogenic constriction in arterioles [2]. We also present the development of a software tool to perform a spatial analysis of the hemodynamic results. This tool provides local information about the flow properties within a spatial microvessel network map in order to optimize the comparison with experiments. A review can be found in [4].

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© 2013 ASME

Published in final form at:

Frank G. Jacobitz, Niki L. Yamaura, and Geert W. Schmid-Schonbein, "Spatial Analysis of the Microcirculation in Rat Spinotrapezius Muscle Fascia," Proceedings of the ASME 2013 Summer Bioengineering Conference, Sunriver, Oregon, 2013.