Date of Award
Undergraduate Honors Thesis
Bachelor of Arts in Biochemistry
Chemistry & Biochemistry
The sodium-hydrogen exchanger isoform 1 (NHE1) is a ubiquitously expressed transmembrane transporter protein involved in regulating intracellular pH and interacts with a variety of proteins involved in cell signaling, proliferation, and cell motility. The protein has an extended cytosolic tail known as the regulatory region. This project investigates the role of palmitoylation, a reversible fatty acid modification on cysteine amino acids, in the function and behavior of NHE1.
Digital USD Citation
Pitsch, Emily, "Palmitoylation of the sodium hydrogen exchanger isoform 1 (NHE1): a novel post-translational protein modification and its regulation of NHE1" (2018). Undergraduate Honors Theses. 53.